The following instructions demonstrate how to find significant CATH structural domain matches on your own protein sequence.The Windows Subsystem for Linux feature may be disabled during a Windows update.
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WSL install will try to automatically change the Ubuntu locale to match the locale of your Windows install.
If you do not want this behavior you can run this command to change the Ubuntu locale after install completes.
Protein structure is nearly always more conserved than sequence.
As a result, when two proteins share a significant sequence similarity, it is extremely likely they will also share similar 3D structure.
While averaging is going on the unit will display a FOM, figure of merit, number to indicate the probable accuracy of the average to this point.