You play it like an old first-person dungeon explorer, only with random naked chicks to play with.
The sequel is more of the same, with a more convenient map and animations in some scenes. There's a limit to how long you can maintain the pocket world that serves as your hunting grounds, and losing fights or letting your girls escape depletes it.
It creates some funny and enjoyable scenarios and some sweet 3D hentai scenes; it's actually pretty complex (and over 6gb). A sequel of this game known as Artificial Academy 2 was released on 2014. Artificial Girl 2 and 3 (also called Jinkō Shōjo 2 / 3), are two "3D erotic life simulation games" where you play as a young male on a island full of girls. A not-turn-based RPG hentai game with a good plot and enjoyable kill everything game play.
Probably the most serious game ever done with RPG Maker XP, because it's heavily scripted and the graphics are really professional. You are a yakuza member that just recently got released from jail.
A beat-em-up style vore game where you battle against all kinds of monsters and sexy monster girls (such as lamias, harpies and spider girls).